Directed by:
- Ethan Coen
- Joel Coen
- Cormac McCarthy (novel)
- Joel Coen (screenplay)
- Ethan Coen (screenplay)
- Tommy Lee Jones ... Sheriff Ed Tom Bell
- Javier Bardem ... Anton Chigurh
- Josh Brolin ... Llewelyn Moss
- Woody Harrelson ... Carson Wells
- Kelly Macdonald ... Carla Jean Moss
- Garret Dillahunt ... Deputy Wendell
- Tess Harper ... Loretta Bell
- Barry Corbin ... Ellis
- Stephen Root ... Man who hires Wells
- Rodger Boyce ... Sheriff Roscoe Giddens
- Beth Grant ... Carla Jean's Mother
- Ana Reeder ... Poolside Woman
- Kit Gwin ... Sheriff Bell's Secretary
- Zach Hopkins ... Strangled Deputy
- Chip Love ... Man in Ford
- Eduardo Antonio Garcia ... 'Agua' Man
- Gene Jones ... Gas Station Proprietor
- Myk Watford ... 'Managerial' Victim #1
- Boots Southerland ... 'Managerial' Victim #2
- Kathy Lamkin ... Desert Aire Manager
- Johnnie Hector ... Cabbie at Bus Station
- Margaret Bowman ... Del Rio Motel Clerk
- Thomas Kopache ... Boot Salesman
- Jason Douglas ... Cabbie at Motel
- Doris Hargrave ... Waitress
- Rutherford Cravens ... Gun Store Clerk
- Matthew Posey ... Sporting Goods Clerk
- George Adelo ... Mexican in Bathtub
- Mathew Greer ... Hitchhiking Driver
- Trent Moore ... Nervous Accountant
- Marc Miles ... Hotel Eagle Clerk
- Luce Rains ... Pickup Driver
- Philip Bentham ... Border Bridge Youth #1
- Eric Reeves ... Border Bridge Youth #2
- Josh Meyer ... Border Bridge Youth #3
- Chris Warner ... Flatbed Driver
- Brandon Smith ... INS Official
- Roland Uribe ... Well Dressed Mexican
- Richard Jackson ... Chicken Farmer
- Josh Blaylock ... Boy on Bike #1
- Caleb Jones ... Boy on Bike #2
- Dorsey Ray ... Odessa Cabbie
- Angel H. Alvarado Jr. ... Norteño Band
- David A. Gomez ... Norteño Band
- Milton Hernandez ... Norteño Band
- John Mancha ... Norteño Band
- Scott Flick ... Cab Driver
- Elizabeth Slagsvol ... Nurse
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